Transcribed Image Text: a. Using Table 10.1, identify the diseases that result when the filtration membranes within the kidneys become damaged and are unable to

Transcribed Image Text: a. Using Table 10.1, identify the diseases that result when the filtration
membranes within the kidneys become damaged and are unable to restrict
or regulate the movement/filtration of larger substances.
b. What kinds of disorders cause damage to the filtration membrane?
ABNORMAL
CONDITION
CAUSE
COMPONENT
Caused by glucose levels in the blood that
exceed the renal tubule’s ability to reabsorb
it. It is a common sign of diabetes mellitus.
Glucose
Glycosuria or
Glucosuria
Albumin
Albuminuria
Caused by damage to the glomerular
and resulting in the
leakage of large quantities of protein,
including albumin, into the filtrate.
filtration mer
Red blood cells
Caused by damage to the glomerular
filtration membrane, allowing whole cells
from the blood to pass into the filtrate.
Hematuria
Hemoglobinuria
Caused by the hemolysis of red blood cells
within the bloodstream, which releases
hemoglobin into plasma that crossek the
glomerular filtraton membrane during
Hemoglobin
renal filtration. Diseases that cause red
blood cell hemolysis include hemolytic
anemia, glomerulonephritis, transfusion
reactions, and burns.
Ketone bodies
While very small levels in the urine are
normal, higher levels are caused by
Ketonuria
abnormalities in metabolism as a result
of enzyme deficiencies, starvation, diets
extremely low in carbohydrates, or
diabetes mellitus.
White blood cells
Pyuria
Caused by inflammation of one or more
organs of the urinary system, often as a
reaction to infection.
A cast consists of aggregated collections of
protein, cells, or cell fragments within the
nephron or renal tubule, caused by disease
and an abnormally low filtration rate, low pH,
or high salt concentration of the filtrate.
Casts
Casts
Bacteria in the urine is a sign of a urinary
tract infection, or UTI.
Bacteria
Bacteriuria
L.

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